On the other hand, type 2 diabetic patients may face some problems to the patients related to their disease and medications. One of the most common comorbidities was hypertension that may lead to other cerebrovascular diseases in the future. The situation may lead to higher risk of DTPs. These studies showed that 46.3% of participants were DM at their initial diagnosis and develop HTN later in their life, 36.9% were DM with HTN at their initial diagnosis, and 16.
7% patients were hypertensive at their initial diagnosis and develop DM later in their life. Pattern of prescription from the study showed an average number of 3.9 drugs per prescription with some prescriptions containing up to 8 drugs per patient, giving an indication of Polypharmacy, which increases the risk of DTP such as adverse drug reaction. Polypharmacy is strongly associated with DTPs with evidence that a one unit increase in the number of drugs can lead to an increase of 8.6% in the number of DTPs (11).