On Friday, January 19th, a graduating seniorKennedy Goldsborough did a presentation on mitochondrial protein homeostasis inperipheral axons. Kennedy Goldsborough is a biochemistry major. Kennedyconducted all of her research at Harvard Medical School and at the BostonChildren’s Hospital. The purpose of her research was to screen newmitochondrial protein synthesis and to select if there will be an expansion ordecline in mitochondrial rates. An axon is a long, slim projection of a nervecell, or neuron, that normally leads electrical driving forces known asactivity possibilities, far from the nerve cell body.
The purpose of the axonis to transmit data to various neurons, muscles, and organs. In order toconduct this experiment, Kennedy used TFB2M cells as her mitochondria sample. TFB2M(Transcription Factor B2, Mitochondrial) is a protein coding gene. Thistranscription aspect triggers transcription of human mitochondrial DNA. Beforedirecting the research, she needed to advance haloblock with the goal that theperfect measure of halotag was included. The following thing done was the TFB2Mwas added to the neurons of the protein. By doing this, she could distinguishthe distinctive proteins from one another.
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Kennedy’s research was unable to befinished but rather she expressed what her further plans were. These designsincluded evaluating the mitochondria and contrasting the rates of the synthesisin the soma versus in distilled cells. The soma or cyton, or “cellbody” is the bulbous, non-process segment of a neuron or other mind cellcompose, containing the cell nucleus. “Soma” originates from theGreek word, signifying “body”. Kennedy’s research was veryintriguing to me because it could definitely be used in the medical field whenespecially dealing with diseases that kill axons. Although her research was notcompleted, it was still an interesting topic. One of the things that I wouldcritique with her presentation was the way she answered some of the questions.
Itsounded as if she wasn’t really sure of the answer. She was unable to answer afew of the questions. I look forward to listening to the next presentation onFriday, January 26th.