Mr. experiments. ” They made a very simplenucleic

Mr. Perry6 December 2017Marshall Warren NirenbergThe long-lived biochemist and geneticist Marshall Warren Nirenberg left us on January15, 2010. Marshall Warren Nirenberg lived a full eighty-three years of life and almost half ofthem were spent studying different sciences. He was originally born in New York City in 1927and the family moved down to Orlando, Florida in 1939. At a very young stage in life, Marshallgrew attached to the study of biology. He received both his bachelors and masters degree fromthe University of Florida. His master’s degree was in Zoology, and his thesis for his masters wasregarding the study of the caddis fly. In 1957 he earned his Ph.D. from the Department ofBiological Chemistry apart from the University of Michigan.In 1960 he got a job as a research biochemist at the National Institutes of Health in theSection of Metabolic Enzymes, in charge of him was Dr. Gordon Tompkins. By 1962 he wasgiven the role as head of the Section of Biochemical Genetics at the National Institutes of Health.Before he received the job he started studying DNA, RNA, and protein in 1959. While in hisstudied he found out the different forms of RNA and their purpose.Marshall Warren Nirenberg along with his colleague Johann H. Matthaei tried to figureout how the genetic information stored in DNA could be laid out as proteins. Their experimentsthey used were called ‘cell-free’. The two put together materials they thought were necessary forprotein synthesis. In a series of observations so they could see which amino acids particularnucleotide templates gave back to. An article by Lotta Fredholm( goes into thespecifics of how they conducted and the outcome of the experiments. ” They made a very simplenucleic acid, composed of a chain of only one single, repeated letter – the nucleotide uracil, or U.Using this nucleic acid, the system produced a protein that also contained a single letter, but nowwritten in the protein language: the amino acid F, phenylalanine. By showing that a strand of Utriplets was indeed the template for the amino acid phenylalanine they cracked the first letter ofthe code.”(Lotta Fredholm)After this information was released to the public Marshall Warren Nirenberg was flownout to Moscow, Russia for a conference. While there Matthaei, who was working in the US,called Nirenberg to tell him CCC was most likely the template for an amino acid call proline(p).In 1968 Marshall Warren Nirenberg, Har Gobind, Khorana, and Robert Holley shared the NobelPrize Physiology or Medicine.


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