Received 5 February 2014
Accepted 5 August 2014
Background: Delivery by caesarean section (CS) is becoming more frequent.
Childbirth is an emotion-filled event, and the mother needs to bond with her
baby as early as possible. Any intervention that leads to improvement in pain
relief is worthy of investigation. Local anaesthetics have been employed as an
adjunct to other methods of postoperative pain relief.
Objective: To insure
the efficacy of infiltration of lidocaine 1% in the surgical site of Cesarean
Section, just before incision ,in decreasing postoperative pain , in comparison
to other forms of preemptive analgesia that includes central nerve block
(spinal anesthesia) , and multi modal parentral analgesia.
Patients and Methods: This is a prospective, randomized, controlled trial
study in which patients undergoing CS were randomly divided into four groups;-
Group A Patients (control
plain GA), Group B Patients with multi modal analgesia Group C Patients with
local tissue infiltration,Group D Patients with spinal anesthesia .
The protocol for induction and maintenance of
general anaesthesia was similar for A , B&C groups. Group A control
patients (plain GA) without supplementary analgesia.
Group B parentral multi
modal analgesia(Acetamenophen&Diphene) given IM. just pre operatively , and
a Fentanyl 50Mg IV. just after delivery of the baby.
patients received 20 ml of 1% Lidocaine
infiltration 1-2 minutes
before skin incision.
Group D have Spinal Anesthesia under Bupivacaine hyperbaric 0.5% 10mg intrathecally. Post-operative pain was evaluated in patients, at 30 min, 2,
4, 6 and 24 hr after surgery by visual analogue score (VAS), while lying still,
and with movement. Time of first request for analgesia , and total
amount of Pethidine consumed in 24 hr were recorded.
Results: The study enrolled a total number of 100 patients, 25 in each group. No
side effects were recorded in all groups.
consumption of opioid (pethidine) after 24
hours was significantly different
among the four groups
144.00mg in group A, 134.00mg in group B, 96.00mg
in group C and 76.00mg in group D (P ? 0.05), SD= 54.619 , 47.258, 37.697,
35.707 for Group A,B,C and D respectively.
Higher dose of analgesia was used by Group A&B, whereas
lower dose used by Group C&D, so there are significant differences (p?0.01)
between the last two motheds than the former two methods.However the lowest
dose was recorded in the spinal anaesthesia.
The first request for opioid
was statistically different among the four groups .